Blastocyst culture
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Think of blastocyst culture as giving embryos the time they need to prove themselves. Here’s what happens: after eggs are retrieved and fertilized in the lab, we keep those embryos growing for 5 to 6 days until they reach the blastocyst stage. At this point, the embryo contains 100 to 200 cells and is ready to implant into your uterine lining.
Why does this matter? In a natural pregnancy, the egg gets fertilized in the fallopian tube, then takes several days to travel to the uterus. During that journey, it develops from a simple two-cell embryo into a blastocyst. When we recreate this process in the lab, we can watch how well each embryo develops and choose the strongest ones for transfer.
A blastocyst has two distinct parts:
* The trophectoderm (outer layer) that helps with implantation
* The inner cell mass (the cells that will actually become your baby)
How Blastocyst Development Works
After egg retrieval, your embryos go through several critical stages in our laboratory incubator:
Day 0: The day we retrieve your eggs
Day 1: We check to see which eggs fertilized successfully (the pronuclear stage)
Day 2: Embryos reach the 2 to 4-cell stage
Day 3: Now we’re looking at 8-cell embryos
Day 4: The morula stage, where cells start compacting together
Day 5 or 6: The blastocyst stage—this is what we’re aiming for
Not every embryo makes it to day 5 or 6. That’s actually valuable information. The embryos that do reach the blastocyst stage have shown they can develop properly, which means they have a better chance of leading to pregnancy.
To know more Call 8448841271 or email us at info@ekmifertility.com
The Blastocyst Culture Process at Ekmi Fertility
Step 1: Fertilization
We fertilize your eggs using either standard IVF treatment (mixing eggs and sperm in a dish) or ICSI (directly injecting a single healthy sperm into each egg). This happens on the same day as your egg retrieval.
Step 2: Incubation
Your fertilized eggs go into specialized culture media that contains all the nutrients embryos need to grow. Then we place them in an incubator that mimics conditions inside your body, the right temperature, humidity, and gas levels.
Step 3: Monitoring
Our embryologists check on your embryos regularly under a microscope. We’re tracking growth patterns, assessing quality, and making sure development is progressing as expected. By day 5 or 6, we can see which embryos have developed into blastocysts.
Step 4: Selection and Transfer
We select the highest quality blastocyst for transfer. Using a thin catheter guided by ultrasound, we place the blastocyst into your uterus. The procedure is quick and doesn’t require anesthesia.
To know more Call 8448841271 or email us at info@ekmifertility.com
Why Blastocyst Culture Improves IVF Outcomes
The benefits are real and measurable:
Better implantation rates: Blastocysts have a significantly higher chance of implanting compared to day 2 or day 3 embryos. They’re more developed and ready to attach to your uterine lining.
Fewer multiple pregnancies: When we can identify the strongest embryo, we can transfer just one instead of two or three. This reduces your risk of twins or triplets, which come with higher rates of pregnancy complications.
More embryos to freeze: Since we typically transfer just one blastocyst, you’ll likely have other quality embryos to freeze for future cycles. This gives you additional chances at pregnancy without going through another full IVF cycle.
Natural selection: By allowing embryos to grow to day 5 or 6, we let biology do some of the selection work. Embryos with genetic abnormalities often stop developing before the blastocyst stage.
To know more Call 8448841271 or email us at info@ekmifertility.com
Who Should Consider Blastocyst Culture?
This approach works particularly well for:
Patients with previous failed IVF cycles: If earlier transfers didn’t work, blastocyst culture gives us more information about how your embryos develop and can improve your chances.
Those wanting to avoid multiple pregnancies: If twins or triplets aren’t what you’re hoping for, blastocyst culture allows us to confidently transfer a single embryo with good success rates.
Women with several good-quality embryos: You need enough fertilized eggs to make it worthwhile to wait until day 5 or 6, since not all embryos will reach the blastocyst stage.
What This Means for Your IVF Journey
Blastocyst culture represents a more selective approach to embryo transfer. Instead of transferring embryos early and hoping for the best, we give them time to show us their potential. The embryos that make it to the blastocyst stage have already cleared several developmental hurdles.
At the best fertility centre in India, we use advanced incubation systems and carefully formulated culture media to support your embryos through this critical development period. Our embryologists have the training and experience to identify the subtle differences that indicate which blastocysts have the best chance of success.
Every IVF cycle is different, and blastocyst culture isn’t right for everyone. During your consultation, we’ll discuss your specific situation, egg reserve, previous cycles (if any), and help you make the decision that gives you the best chance of bringing home a healthy baby.
The goal isn’t just pregnancy, it’s a healthy singleton pregnancy that leads to the family you’ve been hoping for.
To know more Call 8448841271 or email us at info@ekmifertility.com