For couples facing repeated IVF failures despite good quality embryos, the answer might lie in timing. At Ekmi Fertility, we use the ERA test (Endometrial Receptivity Analysis) to solve one of the most frustrating puzzles in fertility treatment: why perfectly healthy embryos fail to implant. This advanced diagnostic tool has transformed success rates for many of our patients.
What is ERA Test in IVF treatment?
The ERA test is a molecular diagnostic tool that analyzes your endometrial tissue to determine the exact window when your uterus is most receptive to embryo implantation. Think of it as finding the precise moment your uterine lining is ready to accept an embryo. This window, called the “window of implantation,” varies from woman to woman and can be shifted by 24-48 hours from the standard timing.
The test examines the expression of 238 genes in your endometrial lining to create a personalized embryo transfer timeline. Instead of following the standard protocol, your doctor can transfer embryos at the exact moment your body is biologically ready.
Who Needs an ERA Test?
Not everyone requires ERA testing. At best fertility centre in India, we recommend this test for specific situations:
Repeated Implantation Failure: If you’ve had two or more failed IVF cycles with good quality embryos, this test can identify if timing is the issue.
Recurrent Miscarriages: When pregnancies don’t progress despite successful implantation, a displaced implantation window might be involved.
Unexplained Infertility: If all other fertility factors appear normal but conception isn’t happening, ERA provides answers.
Before First IVF Cycle: Some couples opt for testing proactively, especially those with limited embryos or advanced maternal age, to maximize first-cycle success.
To know more Call 8448841271 or email us at info@ekmifertility.com
How Does the ERA Test Work?
The procedure is straightforward and performed in our clinic. Here’s the step-by-step process:
You’ll undergo a mock embryo transfer cycle using the same hormone protocol planned for your actual IVF treatment. On the day when embryo transfer would typically occur, your doctor performs an endometrial biopsy. This takes just a few minutes and involves collecting a small tissue sample from your uterine lining.
The sample goes to a specialized laboratory where genetic analysis identifies whether your endometrium is receptive, pre-receptive, or post-receptive at that specific time. Results typically arrive within 2-3 weeks.
Based on findings, your fertility specialist adjusts the progesterone administration timing for your actual embryo transfer. If your window is displaced, the transfer gets scheduled accordingly to match your personalized receptive period.
Success Rate and Benefits
Studies show that ERA testing significantly improves pregnancy rates in women with recurrent implantation failure. Success rates increase by approximately 25-30% when embryo transfer timing is personalized based on these results.
The benefits extend beyond improved conception rates. You avoid the emotional and financial toll of repeated failed cycles. Each IVF attempt becomes more strategic and informed. For couples with limited embryos, ERA ensures those precious embryos are transferred at the optimal moment.
Test Cost in India
At Ekmi Fertility, ERA test costs typically range from Rs. 40,000 to 60,000, including the biopsy procedure and genetic analysis. While this represents an additional expense, many couples find it worthwhile given the cost of repeated IVF cycles. The investment often pays off by reducing the number of cycles needed to achieve pregnancy.
To know more Call 8448841271 or email us at info@ekmifertility.com
Is ERA Test Painful?
The endometrial biopsy causes mild discomfort similar to menstrual cramping. Most women describe it as tolerable, lasting only a few minutes. We recommend taking over-the-counter pain medication beforehand. Some spotting afterward is normal and resolves within a day or two.
Our Approach at Ekmi Fertility
We don’t recommend ERA testing for everyone because not every case requires it. Our fertility specialists carefully evaluate your history, previous IVF attempts, and embryo quality before suggesting this test. When it is appropriate, we handle the entire process in-house, from the biopsy to result interpretation and personalized treatment planning.
Our goal is maximizing your chances of success while minimizing unnecessary procedures and expenses. ERA testing represents one of many advanced tools we use to personalize your fertility journey.
If you’ve experienced repeated IVF failures or want to optimize your chances before starting treatment, schedule a consultation with our specialists to discuss whether ERA testing is right for you.
To know more Call 8448841271 or email us at info@ekmifertility.com
FAQs
What is ERA test and why is it important in IVF?
ERA (Endometrial Receptivity Analysis) is a genetic test that identifies the exact time your uterine lining is most receptive to embryo implantation. ERA personalizes your embryo transfer timing, significantly improving success rates for those with repeated failures.
How accurate is the ERA test for implantation?
The ERA test has approximately 88-92% accuracy in determining endometrial receptivity status. This high accuracy level makes it a reliable tool for timing embryo transfer.
Can ERA test be done during natural cycle?
Yes, ERA testing can be performed during a natural cycle if you ovulate regularly. However, most fertility clinics, including Ekmi Fertility, prefer doing ERA in a hormone-controlled cycle that mimics your planned IVF protocol.
Is ERA test necessary for first IVF cycle?
ERA testing isn’t typically necessary for your first IVF cycle unless you have specific risk factors like advanced age, limited embryos, or known endometrial issues.
What happens if ERA test shows non-receptive endometrium?
If your ERA test shows a non-receptive (pre-receptive or post-receptive) endometrium, your doctor adjusts progesterone timing for your next embryo transfer. The lab report provides specific recommendations for how many hours to shift your transfer, creating a personalized implantation protocol.
To know more Call 8448841271 or email us at info@ekmifertility.com